Amaphilisi okwamanje angelinye lamafomu omthamo asetshenziswa kakhulu, anomphumela omkhulu kakhulu futhi asetshenziswa kakhulu.Inqubo ye-granulation evamile emanzi iseyinqubo evamile ekukhiqizweni kwemithi.Inezinqubo zokukhiqiza ezivuthiwe, ikhwalithi enhle yezinhlayiyana, ukusebenza kahle kokukhiqiza okuphezulu, kanye nokubumba kokucindezelwa.Izinzuzo ezinhle nezinye, yiyona esetshenziswa kakhulu embonini yezemithi.
Inqubo yokukhiqiza amaphilisi ngokuvamile ingahlukaniswa ngokucutshungulwa kwezinto ezingavuthiwe neziyisizayo, ukukala, ukugoqa, ukomisa, ukuxuba, ukufakwa kwethebhulethi, ukumboza, njll. Kunesisho embonini esithi: i-granulation ingumholi, ithebhulethi ingumgogodla, futhi ukupakishwa kungumsila we-Phoenix, kungabonakala ukuthi inqubo ye-granulation idlala indima ebalulekile kuwo wonke ukukhiqizwa kwethebhulethi, kodwa indlela yokwenza izinto ezithambile futhi uthole ama-granules, kuze kube manje kunencazelo ejulile kakhulu ezincwadini zokufunda ibhola, ukuthinta nokuhlakaza” , Akukakacaciswa.Ngokusekelwe kokuhlangenwe nakho kombhali ekukhiqizeni kwangempela, lesi sihloko sihlaziya izici ezimbalwa ezivamile ezithinta ukuzinza kwenqubo ye-tablet ye-granulation emanzi, futhi iphakamisa izinyathelo zokulawula ezifanele zokuqinisekisa ikhwalithi yokukhiqizwa kwezidakamizwa.
Ukwelashwa kwangaphambili kwezinto zokusetshenziswa
Izinto ezingavuthiwe neziyisizayo ngokuvamile zidinga ukuchotshozwa futhi zihlolwe ngaphambi kokuxutshwa okumanzi nokukhiqizwa kwegranulation.Ezinye izigigaba ezingafanelekile ezivame ukwenzeka ngenqubo yokufakwa kwamathebulethi, njengokuxutshwa kokungalingani, ukuhlukaniswa, ukunamathela noma ukuhlakazwa, njll., zihlobene eduze nokucoliseka okunganele kokucwenga kwezinto zokusetshenziswa ngesikhathi sokwelashwa kusengaphambili.Uma izinto zokusetshenziswa zingama-scaly noma amakristalu amise njengenaliti, kungenzeka ukuthi ukuphambuka okungenhla kuzoba sobala kakhulu.Isikrini sokwelashwa kwangaphambili, ukuchotshozwa kanye nokusefa inqubo evamile ngokuvamile isikrini se-mesh engu-80 noma i-100 mesh, kodwa ngokuthuthukiswa kwemishini kanye nobuchwepheshe bempahla eluhlaza, izinto eziningi zokusetshenziswa ezichotshoziwe ngesikrini se-mesh engu-80 ngenqubo evamile. manje ingadlula i-100. Amathuba ale nto engenhla ancishiswa kakhulu kumpushana ocolekile ochotshoziwe ngesihlungo se-100-mesh.Ngakho-ke, ubuhle bezinto ezingavuthiwe neziyisizayo ngokusebenzisa isisefo se-100-mesh kancane kancane kungena esikhundleni senqubo ye-80-mesh sieving.
Ukukala
Ngoba ukwanda noma ukuncipha kwesisindo sento ngayinye kuzodala izinguquko ezilandelanayo kwezinye izimo zenqubo, ezizobangela ukuntengantenga kwekhwalithi yezinhlayiyana, okungase kubangele uchungechunge lwezinkinga ezifana nokuchopha kwethebhulethi, ukugobazeka okukhulu, ukuwohloka kancane noma ukuncipha. ukuhlakazeka, ngakho ngaso sonke isikhathi uma uphakela Inani alikwazi ukuguqulwa ngokuzenzakalelayo.Uma kunezimo ezikhethekile, isisindo sokukala kufanele siqinisekiswe ngokuvumelana nokuqinisekiswa kwenqubo.
Ukulungiswa kwezinhlayiya
Namuhla, i-granulator yokuxuba okumanzi ngesivinini esiphezulu iyithuluzi elisetshenziswa kakhulu ekukhiqizeni i-granulation.Uma kuqhathaniswa ne-mixer ne-granulator evamile, lolu hlobo lwe-granulator empeleni lungenxa yenkinga yemithi ehlukahlukene noma ukuphishekela ikhwalithi ephezulu.Ngakho-ke, i-granulator ayiqediwe, futhi i-granulator yokuxuba okumanzi ngesivinini esiphezulu isetshenziswa kuphela njengengxube yendabuko, bese kutholakala ama-granules amaningi afanayo ngokusebenzisa i-granulation.Izimo zenqubo ezithinta ikhwalithi yama-granules amanzi ikakhulukazi zihlanganisa izici eziningi ezifana nezinga lokushisa, umthamo, indlela yokwengeza ye-binder, isivinini esishukumisayo nokusika se-granulator, kanye nesikhathi sokunyakazisa nokusika.
Izinga lokushisa le-adhesive
Izinga lokushisa le-adhesive liyipharamitha yenkomba enzima kakhulu yokulawula ekukhiqizeni isikali.Cishe akunakwenzeka ukulawula ngokunembile ukuhambisana kwezinga lokushisa ngaphambi kokwengeza okunamathelayo ngaso sonke isikhathi.Ngakho-ke, izinhlobo eziningi ngeke zisebenzise izinga lokushisa njengenkomba yokulawula, kodwa ekukhiqizeni kwangempela, kutholakala ukuthi izinga lokushisa le-starch slurry linomthelela omkhulu kwezinye izinhlobo ezikhethekile.Kulezi zinhlobonhlobo, izinga lokushisa lidinga ukudingeka ngokucacile.Ngaphansi kwezimo ezijwayelekile, izinga lokushisa liphezulu.Ukuphakama kokunamathela okuphansi, i-tablet iyancipha i-friability;izinga lokushisa le-starch slurry liphezulu, i-adhesion ephansi, futhi iphezulu ukuhlakazeka kwethebhulethi.Ngakho-ke, kwezinye izinqubo ezisebenzisa isitashi slurry njengesibophezelo, izinga lokushisa le-binder kufanele lilawulwe ngezinga elithile.
Inani lokunamathela
Inani le-binder linomphumela osobala kakhulu ezinhlayiyeni ezimanzi, ngakho-ke inani layo libuye lisetshenziswe njengepharamitha yokulawula ebalulekile.Ngokuvamile, uma likhulu inani le-binder, ukuphakama kwezinhlayiyana nobulukhuni kuyaphakama, kodwa inani le-binder livame ukuhluka ngeqoqo lezinto ezingavuthiwe neziyisizayo.Kuzophinde kube noshintsho oluncane umehluko phakathi kwezinhlobo ezahlukene, okudingeka ziqoqwe ohlelweni lwesikhathi eside lokukhiqiza ngokwezinhlobo ezahlukene.Ukuze kulungiswe ukuqina kwezinto ezithambile, ngaphakathi kwebanga elifanele, indlela yokwandisa inani le-binder ingcono kunendlela yokwandisa isikhathi sokuxuba.
Ukugxila kokunamathela
Ngokuvamile, ukugxila okukhulu kwe-adhesive, kukhulu i-viscosity, engenakuhlukaniswa nomthamo wayo.Abakhiqizi abaningi ngeke bakhethe ukulungisa ukugxila lapho bethola ukugxila kokunamathela ngemuva kokuqinisekisa, kodwa balawule izinto ezithambile ngokulungisa inani le-adhesive, ngokuvamile ebophayo. ngeke isetshenziselwe ukulungisa ikhwalithi yezinhlayiya ezimanzi, ngakho-ke ngeke ngikuphinde lapha.
Indlela yokwengeza i-adhesive
Sebenzisa umshini we-granulation omanzi oxuba ngesivinini esiphezulu ukuze wenze i-granulate.Ngokuvamile, kunezindlela ezimbili zokwengeza i-binder.Enye iwukumisa umshini, uvule ikhava ye-granulator, futhi uthele i-binder ngqo.Ngale ndlela, i-binder akulula ukuyihlakaza, futhi i-granulation ngezinye izikhathi kulula ukubangela ukuhlushwa okuphezulu kwendawo kanye nokuqina kwezinhlayiyana ezingalingani.Umphumela wukuthi amaphilisi akhishwe ahlakazeka noma ahlakaze umehluko omkhulu;enye yisimo esingami, kusetshenziswa i-binder feed hopper, ukuvula ivalve yokudla, nokunyakazisa.Ukwengeza kule nqubo, le ndlela yokudla ingagwema ukungalingani kwendawo futhi yenze izinhlayiya zifane kakhulu.Kodwa-ke, ngenxa yezidingo zohlobo lwe-binder, idizayini yemishini noma imikhuba yokusebenza, njll., ikhawulela ukusetshenziswa kwendlela yesibili yokulutha ekukhiqizeni.sebenzisa.
Ukukhethwa kwejubane lokuxuba nesivinini sokusika
Ukwakheka kwezinto ezithambile ngesikhathi se-granulation kuhlotshaniswa ngokuqondile nokukhethwa kwesivinini esishukumisayo nokusika kwe-granulator yokuxuba ngesivinini esikhulu, enomthelela omkhulu kwikhwalithi yama-pellets, futhi ithinta ngokuqondile ikhwalithi yamaphilisi akhishwe.Njengamanje, injini enyakazayo yegranulator yokuxuba okumanzi enesivinini esikhulu inezivinini ezimbili nokulawulwa kwesivinini esishintshashintshayo.Ijubane eliphindwe kabili lihlukaniswe ngesivinini esiphansi kanye nesivinini esikhulu.Ukulawula isivinini sokuguqula imvamisa kusebenzisa ukulawula isivinini okwenziwa ngesandla, kodwa ukulawulwa kwejubane okwenziwa ngesandla kuzothinta izinhlayiya ngokwezinga elithile.Ngakho-ke, i-granulator yokuxuba enesivinini esikhulu enomthethonqubo wesivinini sokuguqulwa kwemvamisa ngokuvamile ibeka isivinini sokuxuba nesikhathi sokusebenza, futhi iqala uhlelo lokusebenza oluzenzakalelayo ukuze kuncishiswe umehluko womuntu.Ezinhlobonhlobo zomuntu ngamunye, ukuguqulwa kwemvamisa zisasetshenziswa njengejubane elibili, kepha kwezinye izinhlobo ezikhethekile, ezisebenza ngasikhathi sinye, ungakhuphula ijubane ukuze uthole izinto ezithambile ezimaphakathi, ukuze ugweme ukuxubana kwesikhathi eside okubangelwa impahla ethambile iqine kakhulu.
Ukukhetha isikhathi sokuxuba nokusika
Ipharamitha yenqubo ethinta ikhwalithi yezinto ezithambile yisikhathi sokuxuba nokusika.Ukulungiselelwa kwemingcele yayo kunquma ngokuqondile impumelelo noma ukwehluleka kwenqubo ye-granulation.Nakuba isivinini sokuxuba kanye nesivinini sokugaya singashintshwa ukuguqulwa kwemvamisa, izinketho eziningi zenqubo zilungiswa Ukuze unciphise umehluko, ukuze uthole ukwaziswa okuthambile okufanelekile, khetha ukuthola izinto ezithambile ezifanele ngokulungisa isikhathi.Ngaphansi kwezimo ezijwayelekile, ukuxubana okufushane kanye nesikhathi sokuhlakaza kuzonciphisa ukuminyana, ubulukhuni, nokufana kwezinhlayiya, nokuqhekeka kanye nokufana okungafanelekile ngesikhathi sokubhebhetheka;isikhathi eside kakhulu sokuxuba kanye nokuhlakazeka kuzodala ukuminyana nobulukhuni bezinhlayiya Uma kunyuswa, izinto ezithambile zingase zehluleke ngesikhathi sokucindezelwa kwethebhulethi, isikhathi sokuhlakazeka kwethebhulethi sizokwelulwa, futhi izinga lokuqedwa ngeke lifaneleke.
Imishini ye-granulation kanye namasu we-granulation
Njengamanje, ukukhethwa kwemishini yokugaya ye-granulation emanzi ihlukaniswe nge-multi-function granulator kanye ne-swing granulator.Izinzuzo ze-multi-function granulator ukusebenza kahle okuphezulu nokusebenza okulula nokusetshenziswa.Ububi buwumehluko enanini kanye nesivinini sokuphakela ngenxa yokuphakelwa mathupha., Ukufana kwezinhlayiya kubi kakhulu;inzuzo yohlobo lwe-swing granulator ukuthi ama-granules ayafana, futhi umehluko enani lokudla okwenziwa ngesandla kanye nesivinini sokuphakela sincane.Okubi ukuthi ukusebenza kahle kuphansi futhi ukusetshenziswa kwezikrini ezilahlwayo kusetshenziselwa ukuhlakazwa.Ukufaka akulula kangako.Usayizi wezinhlayiyana ongalingani ungabangela kalula ukuthi umehluko weqe umkhawulo.Inombolo yemeshi nesivinini saso sonke isikrini sezinhlayiyana singalawulwa ukuze sithuthuke.Ngokuvamile, uma izinhlayiya ezimanzi ziqinile, ungacabangela ukukhulisa isivinini, ukukhetha isikrini esikhulu, nokunciphisa inani lokuphakelayo isikhathi ngasinye.Uma izinhlayiya zixega, ungacabanga ukunciphisa isivinini, ukhethe isikrini esincane, futhi wandise inani lokuphakelayo isikhathi ngasinye.Ngaphezu kwalokho, ekukhetheni izikrini, kuvame ukuba nezikrini zensimbi engagqwali nezikrini zenayiloni ongakhetha kuzo.Ngokusho kokuhlangenwe nakho kokukhiqiza kanye nezakhiwo zezinto ezithambile, kungcono ukukhetha izikrini zensimbi engagqwali zezinto ezithambile ze-viscous, nezinto ezomile ezithambile.Isikrini senayiloni sifaneleka kakhulu, futhi isicuphi sohlobo lokushwiba singaphinde sicabangele ukucinana kokufakwa kwesikrini ukuze silungise ukuze kutholwe izinhlayiya ezifanele.``
Yomile
Ukubonakaliswa okunembile komphumela wokomisa umswakama wezinhlayiyana.Umswakama wezinhlayiyana uyisici esibalulekile sokuhlola izinga lezinhlayiya.Ukulawula okuphusile kwale pharamitha kuthinta ngqo ukubukeka kanye nokuntenga kwethebhulethi ngesikhathi sokusebenzisa ithebhulethi.Ngaphansi kwezimo ezijwayelekile, ukuvela kokuchotshozwa ngesikhathi sokulayishwa kwethebhulethi kungabhekwa ukuthi kubangelwa umswakama wezinhlayiyana eziphansi, futhi uma ukunamathela kwenzeka ngesikhathi sokubhebhetheka, kuyadingeka ukuthi kubhekwe ukuthi kubangelwa yini umswakama ophezulu wezinhlayiyana.Inkomba yokulawula yomswakama wezinhlayiyana ngokuvamile inqunywa ekuqaleni ngokuqinisekiswa kwenqubo, kodwa umswakama uvame ukuba nzima ukuphinda ukhiqize, futhi kuyadingeka ukuqoqa idatha futhi wenze ububanzi bokulawula umswakama.Izindlela eziningi zokomisa zendabuko zisebenzisa ukomisa ukubilisa.Izici ezinomthelela zihlanganisa imingcele yenqubo efana nomfutho we-steam, izinga lokushisa lokumisa, isikhathi sokumisa, nesisindo sezinhlayiya ezomisiwe.Umswakama wezinhlayiya ulawulwa yi-analyzer esheshayo yomswakama.Umsebenzisi onekhono angadlula isikhathi eside.Ekukhiqizeni, okuqukethwe komswakama wento ngayinye yokomisa kulawulwa ngaphakathi kwebanga elifanele, okungathuthukisa ngempumelelo ukukhiqiza futhi kungalawula kangcono umswakama.Ngokungeziwe kulwazi lwesikhathi eside, umthombo wedatha oyinhloko nesikhathi sokumisa kanye nezinga lokushisa lezinto ezomisiwe.
I-granulation ephelele yama-granules omile
Okufanayo ne-granulation emanzi ukuthi amapharamitha enqubo athinta ikhwalithi yama-granules omile ngokuvamile ayinombolo yemeshi nesivinini saso sonke isikrini se-granulation.Ukuze uqinisekise ukukhiqizwa okubushelelezi ngesikhathi sethebhulethi, thola ukusabalalisa usayizi wezinhlayiyana ezifanele kakhulu.Leli yithuba lokugcina lokulungisa., Ngokukhetha ama-meshes ahlukene kanye nesivinini esijikelezayo, kuzoba nomthelela omkhulu ezinhlayiyeni ezomisiwe.Ngokuvamile, lapho izinhlayiya ziqinile, khetha isikrini esincane, futhi lapho izinhlayiya zikhululekile, khetha isikrini esikhulu.Kodwa-ke, ngaphansi kwezimo ezijwayelekile, lokhu ngeke kube ukukhetha kwenqubo evuthiwe.Uma ufuna ukuthola izinhlayiya ezingcono, kusadingeka ufunde futhi uthuthukise inqubo yokulungiselela izinto ezithambile.
Ukuxuba
Imingcele yenqubo yokuxuba ethinta ikhwalithi yezinhlayiyana ngokuvamile inani lengxube, isivinini se-mixer, nesikhathi sokuxuba.Inani lengxube liyinani elingashintshi ngemva kokuqinisekiswa kwenqubo.Ijubane le-mixer lingase lithinteke ukukhukhuleka kwejubane le-mixer ngenxa yokuguga kwemishini.Ukufana kokuxuba kudinga ukuhlolwa kwendawo yokusebenza kanye nokuqinisekiswa ngezikhathi ezithile kwemishini ngaphambi kokukhiqiza.Ukuze uqinisekise ukufana kokuxuba izinhlayiyana ngezinga elikhulu futhi uthole imikhiqizo yekhwalithi efanayo, kuyadingeka ukuthola isikhathi sokuxuba ngokuqinisekiswa kwenqubo.Isikhathi esanele sokuxuba siyisiqinisekiso esisebenzayo sokuqinisekisa izinga lokuhlakazwa kwe-lubricant ezinhlayiyeni ezomile, ngaphandle kwalokho i-lubricant izokwakha amaqembu e-electrostatic adsorption ngesikhathi sokuxuba izinhlayiya ezomile, okuzothinta ikhwalithi yezinhlayiya.
Isitatimende:
Okuqukethwe kwalesi sihloko kuvela kunethiwekhi yemidiya, ekhiqizwe kabusha ngenhloso yokwabelana ngolwazi, njengokuqukethwe kwemisebenzi, izinkinga ze-copyright, sicela usithinte zingakapheli izinsuku ezingama-30, sizoqinisekisa futhi sikususe ekuqaleni.Okuqukethwe kwe-athikili kungokwababhali, akumeli umbono wethu, akusho noma yiziphi iziphakamiso, futhi lesi sitatimende nemisebenzi inencazelo yokugcina.
Isikhathi sokuthumela: Apr-20-2021