I-CBD Oral Film Product Isingeniso
I-ODF, igama eligcwele ifilimu ehlakazeka ngomlomo.Lolu uhlobo olusha lwefomu lomthamo.
Abantu bafaka ulwelwesi emlonyeni, luzomuncwa ngamathe, luhlakazeke ngokushesha, ukuze umzimba ukwazi ukumunca.
Uma kuqhathaniswa neminye imikhiqizo, lo mkhiqizo wefilimu unezici zokumunca ngokushesha, ukuthwala kalula, impilo yeshelufu ende, futhi asikho isidingo sokuthi ezinye izinto eziwuketshezi zisetshenziswe ndawonye.
Lo mkhiqizo ngokuvamile usebenza ezimbonini ezifana nemithi, imikhiqizo yokunakekelwa kwezempilo, ukudla, kanye nokuphuma kwensangu.
Emashumini ambalwa eminyaka adlule, ukuthambekela ezinhlelweni ezintsha zokulethwa kwezidakamizwa kuye kwakhulisa kakhulu imizamo yokuqinisekisa ukusebenza kahle, ukuphepha kanye nokwamukeleka kwesiguli.Njengoba ukutholwa nokuthuthukiswa kwama-ejenti amakhemikhali amasha kuyinqubo eyinkimbinkimbi, ebizayo futhi edla isikhathi, ngakho izitayela zamuva sezishintshela ekwakhiweni nasekuthuthukiseni izinhlelo ezintsha zokulethwa kwezidakamizwa zemithi ekhona.Kulawo, uhlelo lokulethwa kwezidakamizwa olugqama kakhulu phakathi kwamafilimu ahlakaza ngomlomo (ama-ODF).
Lawa mafilimu ahlakazeka ngokushesha aphakeme kunamaphilisi asheshe ahlakazeka njengoba lawa maphilisi ehlotshaniswa nezingozi zokuklinywa kanye nokuqina.Lolu hlelo lokulethwa kwezidakamizwa lunezinzuzo eziningi ngaphezu kwamaphilisi ajwayelekile ahlakazeka ngokushesha.
Kusetshenziswa izindlela ezahlukahlukene zokwakha ama-ODF futhi phakathi kwazo izindlela zokuncibilikisa nezifutho zisetshenziswa njalo.Ngokuvamile, ama-polymers angama-hydrophilic kanye nezinye izinto ezisizayo asetshenziselwa ukulungisa ama-ODF avumela amafilimu ukuthi ahlakazeke ngokushesha akhiphe isithako semithi esisebenzayo esihlanganisiwe (API) ngemizuzwana.Amafilimu ahlakazeka ngomlomo anamandla okuxhashazwa kwebhizinisi nezimakethe ngenxa yezinkulungwane zezinzuzo zawo ngamaphilisi ahlakazeka ngomlomo.
Umzila womlomo wokuphathwa kwezidakamizwa uyindlela ethandwa kakhulu ngenxa yokuphatha kalula, ukungahlaseli, ukuguquguquka, ukuthobela isiguli nokwamukeleka.Amafomu omthamo we-bioadhesive mucosal afaka amaphilisi okunamathelayo, ama-gel nama-patches ayimiphumela yentuthuko yezobuchwepheshe.Phakathi kwamafomu ahlukahlukene wemithamo, ukusetshenziswa kwamafilimu e-polymeric ekuletheni imithi endaweni ye-buccal kuthuthukise amandla amakhulu enkathini yakamuva (Arya et al., 2010).Amafilimu ahlakazeka ngomlomo (ama-ODF), lapho ebekwe olimini, angena ngokushesha emanzini ngokucwilisa amathe kulandela ukuhlakazeka kanye/noma ukuhlakazeka kukhiphe i-ejenti esebenzayo yemithi efomini lomthamo (Chauhan et al., 2012).Ama-ODF awuhlobo lwezakhiwo ezivame ukulungiselelwa kusetshenziswa ama-polymers angama-hydrophilic avumela ukuqedwa ngokushesha lapho kuthinta amathe.Amaphilisi ahlukanisayo ngomlomo (ama-ODT) namafilimu ahlukanisayo ngomlomo (ama-ODF) ayizibonelo ezijwayelekile zezinhlelo zokulethwa kwezidakamizwa ezihlakazeka ngomlomo.
Ukusetshenziswa kwe-hemp ku-ODF kusesigabeni esisha.Izinto ze-CBD eziqukethwe kufilimu ngayinye zilungisiwe, futhi izingxenye ze-CBD ezidliwayo isikhathi ngasinye nazo ziyalungiswa, okuqinisekisa ukuthi abasebenzisi ngeke badle izinto ngokweqile.Ngesikhathi esifanayo, isici sokuhlakazeka ngokushesha senza izithako ezizuzisayo zihlakazwe ngokushesha futhi zimunce.
